Retinoids during Pregnancy

Pause all retinoids during pregnancy and while trying to conceive.

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pause it for this moment.

Pause all retinoids during pregnancy and while trying to conceive.

how to use it. Stop retinoid products immediately on a positive pregnancy test or when actively trying to conceive; most sources recommend stopping topical retinol at least one month before conception. Azelaic acid 15-20% and bakuchiol are the pregnancy-permissible alternatives; azelaic has the stronger safety record.

why it works. Oral retinoids are established teratogens. Topical absorption is low and a 2025 Nordic cohort study of ~7,000 first-trimester exposures found no increased malformation risk, but ACOG and AAD still recommend avoidance out of caution given the severity of retinoid embryopathy if absorption were meanin...

Reviewed with 5 sources on 2026-07-03.

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