Tranexamic Acid for Melasma
Topical tranexamic acid is a well-supported melasma treatment.
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Topical tranexamic acid is a well-supported melasma treatment.
how to use it. 5% topical twice daily. Comparable efficacy to hydroquinone at 12 weeks (~27% MASI reduction).
why it works. Inhibits plasminogen activation on keratinocytes, reducing UV-triggered melanogenesis.
Reviewed with 2 sources on 2026-07-03.
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